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Lipolysis is a metabolic process in which lipids, or fats, are broken down into constituent components, primarily glycerol, and fatty acids. This process occurs mainly in adipose (fat) tissue and is essential to the body’s energy metabolism. Hormones and enzymes control lipolysis. When energy is needed, hormones like epinephrine, norepinephrine, and glucagon trigger lipolysis, while insulin stops it. They activate an enzyme (HSL) that breaks down fat into glycerol and fatty acids. These components are then used by organs like the liver, muscles, and heart to create energy.

Lipolysis is crucial in providing energy during fasting, exercising, or calorie restriction periods. In these times, lipolysis ensures that the body can maintain essential functions even when food is low, or energy demand is high.


Lipolysis procedure, also known as non-surgical fat reduction or non-invasive body contouring, refers to a group of cosmetic procedures. These procedures are designed to break down and remove fat deposits in the body without the need for surgery. Lipolysis can be an alternative to minimally invasive or invasive procedures such as traditional liposuction procedures.

Lipolysis treatments aim to reduce unwanted fat and improve body contour. Lipolysis treatment mainly operates in areas that resist diet and exercise. Various techniques are used for lipolysis treatment, including:

  • Laser lipolysis: It is a method where the targeted area is treated with a laser. Laser lipo uses low-level laser energy to target and break down fat cells. The damaged fat cells then release their contents, which are naturally eliminated from the body over time. 

Radiofrequency lipolysis: When radiofrequency (RF) energy is applied to the treatment area, it generates heat. This controlled heat damages fat cells and causes them to break down. 

Cryolipolysis: Also known as fat freezing or CoolSculpting, cryolipolysis uses controlled cooling to selectively freeze and destroy fat cells. The destroyed fat cells are then gradually removed from the body through the natural metabolic process. One of the best examples of cryolipolysis is the Clatuu Alpha device.

Injection lipolysis: This technique involves injecting a chemical solution (commonly containing deoxycholic acid) into the treatment site to dissolve fat cells.

Ultrasound lipolysis: High-intensity focused ultrasound (HIFU) energy is used to destroy fat cells selectively. The ultrasound energy penetrates the skin and targets fat cells, causing them to break down. 

It is important to note that lipolysis treatments are not weight loss solutions but rather body contouring procedures. They are most suitable for individuals who are close to their ideal weight but struggle with stubborn fat deposits resistant to diet and exercise. The results of lipolysis treatments can vary, and multiple sessions may be required to achieve the desired outcome. It is essential to consult the goals, outcomes, and side effects of the treatment with your doctor.


Lipolysis treatments are generally suitable for individuals looking to address stubborn fat deposits that have not responded to diet and exercise. Ideal candidates for these non-invasive body contouring procedures typically meet the following criteria:

  • Near their ideal body weight: Lipolysis treatments are not intended for a significant amount of weight loss. They are instead for reducing localized fat and improving body contour. Candidates should be at or near their ideal body weight, with a body mass index (BMI) of 30 or less.
  • Have localized fat deposits: Candidates should have specific areas with stubborn fat that they wish to target. Lipolysis can be used on areas of the body such as the abdomen, flanks, thighs, arms, or under the chin. Lipolysis treatments are not suitable for overall fat reduction.

Good overall health: Candidates should be in good general health and free of any medical conditions. Some medical conditions may increase the risk of complications or affect the healing process.

Realistic expectations: Ideal candidates understand that lipolysis treatments are not a substitute for a healthy lifestyle. Candidates should maintain a balanced diet and regular exercise routine to preserve the results. The patients should have realistic expectations about the outcome. Acknowledge that multiple treatment sessions may be required and that results will likely be gradual and subtle rather than dramatic.

It is essential to consult with a qualified healthcare professional to determine if lipolysis treatments are appropriate for your specific needs and circumstances. They will evaluate your medical history, overall health, and treatment goals to help you decide on the most suitable option.